S Tier
Exile CelestialCatch MultiplierThe premiere endgame bloodline. 2.0x catch on mutated entities makes it the single most valuable passive for players chasing the meta.PicomoriCatch MultiplierPicomori is the most reliable catch multiplier for hidden monster routes. Astral Grove players should reroll aggressively for this.Sealed CalamityHatch BoosterSealed Calamity is the strongest hatch-time bloodline. -25% across all eggs compounds hard over an account lifetime.
A Tier
MilofoyRank LuckMilofoy is the workhorse mid-game bloodline. +100% Rank Luck is the simplest meaningful passive to lock in.Serpent DeityHatch BoosterSerpent Deity is the weaker version of Sealed Calamity but much easier to roll.SnowbloomCatch + Hidden FloorSnowbloom is a stable Iceberg bloodline. Weaker than Picomori but easier to roll and still useful.